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Invitrogen™ WWC1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA572829
This item is not returnable.
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Description
WWC1 Polyclonal Antibody for Western Blot, IHC (P), ELISA
WWC1 (Protein KIBRA) is a probable regulator of the Hippo/SWH signaling pathway. This pathway plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. WWC1, along with NF2, can synergistically induce the phosphorylation of LATS1 and LATS2. It acts as a transcriptional coactivator of ESR1 - which plays an essential role in DYNLL1-mediated ESR1 transactivation. WWC1 also functions as a regulatior of collagen-stimulated activation of the ERK/MAPK cascade.
Specifications
| WWC1 | |
| Polyclonal | |
| Unconjugated | |
| WWC1 | |
| AA408228; AU017197; BC037006; FLJ10865; FLJ23369; HBeAg-binding protein 3; HBEBP3; HBEBP36; Kiaa0869; KIBRA; Kidney and brain protein; MEMRYQTL; mKIAA0869; PPP1R168; Protein KIBRA; protein phosphatase 1, regulatory subunit 168; protein WWC1; RGD1308329; WW and C2 domain containing 1; WW domain-containing protein 1; WW, C2 and coiled-coil domain containing 1; WWC1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 211652, 23286, 303039 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| ELISA, Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| Q5SXA9, Q8IX03 | |
| WWC1 | |
| WWC1 antibody for an 18 amino acid peptide near the amino terminus of human WWC1. The immunogen is within amino acids 60 - 110 of WWC1. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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