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XPF Monoclonal Antibody (OTI2A1), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA503314
This item is not returnable.
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Description
The structure specific ERCC 1 / XPF endonuclease complex is implicated in the repair of two distinct types of lesions in DNA: NER for UV induced lesions and bulky chemical adducts; and recombination repair of the very genotoxic interstrand cross links. NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells, XPG cleaves 3′ of the DNA lesion while the ERCC1 / XPF complex makes the 5′ incision. ERCC1 / XPF probably plays a role in processing partially processed recombination intermediates.Specifications
| XPF | |
| Monoclonal | |
| 0.93 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| Q92889, Q9QZD4 | |
| Ercc4 | |
| Full length human recombit protein of human ERCC4 produced in HEK293 cell. | |
| 100 μL | |
| Primary | |
| Canine, Human, Mouse, Rat | |
| Antibody | |
| IgG2a |
| Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot | |
| OTI2A1 | |
| Unconjugated | |
| ERCC4 | |
| ERCC11, FANCQ, RAD1, XFEPS, XPF | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 2072, 304719, 479842, 50505 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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