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XPF Mouse anti-Human, Clone: OTI6E6, lyophilized, TrueMAB™
Mouse Monoclonal Antibody
Brand: Origene Technologies CF503294
This item is not returnable.
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Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
The structure specific ERCC 1 / XPF endonuclease complex is implicated in the repair of two distinct types of lesions in DNA: NER for UV induced lesions and bulky chemical adducts; and recombination repair of the very genotoxic interstrand cross links. NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells, XPG cleaves 3′ of the DNA lesion while the ERCC1 / XPF complex makes the 5′ incision. ERCC1 / XPF probably plays a role in processing partially processed recombination intermediates.Specifications
| XPF | |
| Monoclonal | |
| Unconjugated | |
| ERCC4 | |
| ERCC11, FANCQ, RAD1, XFEPS, XPF | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 2072 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Lyophilized |
| Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
| OTI6E6 | |
| PBS with 8% trehalose and no preservative; pH 7.3 | |
| Q92889 | |
| ERCC4 | |
| Full length human recombit protein of human ERCC4 produced in HEK293 cell. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2b |
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