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Invitrogen™ XRCC1 Polyclonal Antibody
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Product Code. 15905805
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Quantity:
100 μg
Unit Size:
100µg
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15905805 100 μg 100µg
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Product Code. 15905805 Supplier Invitrogen™ Supplier No. PA580237

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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human Hela whole cell, human 293T whole cell, human K562 whole cell, human Jurkat whole cell, rat brain tissue, rat liver tissue, mouse brain tissue, mouse liver tissue. IHC: rat kidney tissue, human placenta tissue, human colon cancer tissue, human mammary cancer tissue IHC-F: rat intestine tissue, human placenta tissue, mouse intestine tissue. ICC/IF: NIH3T3 cell. Flow: THP-1 cell.

XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair. XRCC1 is a 70 kDa protein that has been shown to be physically associated with other DNA repair enzymes, including poly (ADP-ribose) polymerase (PARP), DNA Ligase III and DNA polymerase beta. XRCC1 contains a BRCT domain (for BRCA1 carboxyl terminus) which was originally found in the tumor suppressor protein BRCA1. Recently, the BRCT domain has been shown to mediate the protein-protein interaction of XRCC1 and DNA ligase III-alpha.
TRUSTED_SUSTAINABILITY

Specifications

Antigen XRCC1
Applications ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and 0.05mg sodium azide
Gene XRCC1
Gene Accession No. P18887, Q60596, Q9ESZ0
Gene Alias DNA repair protein XRCC1; RCC; X-ray repair complementing defective repair in Chinese hamster cells 1; X-ray repair cross complementing 1; x-ray repair cross-complementing group 1 protein; X-ray repair cross-complementing protein 1; XRCC1; Xrcc-1
Gene Symbols XRCC1
Host Species Rabbit
Immunogen E. coli-derived human XRCC1 recombinant protein (Position: E538-A633).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22594, 7515, 84495
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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