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Invitrogen™ XRCC6BP1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand: Invitrogen™ PA588836

Product Code. 16546931

€ 520.00 / 100µL

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Description

Immunogen sequence: MAGAPDERRR GPAAGEQLQQ QHVSCQVFPE RLAQGNPQQG FFSSFFTSNQ KCQLRLLKTL ETNPYVKLLL DAMKHSGCAV NKDRHFSCED CNGNVSGGFD ASTSQIVLCQ NNIHNQAHMN RVVTHELIHA FDHCRAHVDW FTNIRHLACS EVRAANLSGD CSLVNEIFRL HFGLKQHHQT CVRDRATLSI LAVRNISKEV AKKAVDEVFE SCFNDHEPFG RIPHNKTYAR YAHRDFENRD RYYSNI; Positive Samples: Mouse brain, Rat brain.

The protein encoded by this gene is amplified in glioblastomas and interacts with the DNA binding subunit of DNA-dependent protein kinase. This kinase is involved in double-strand break repair (DSB), and higher expression of the encoded protein increases the efficiency of DSB. In addition, comparison to orthologous proteins strongly suggests that this protein is a metalloprotease important in the biosynthesis of mitochondrial ATPase. Several transcript variants encoding different isoforms have been found for this gene.

Specifications

Antigen	XRCC6BP1
Classification	Polyclonal
Conjugate	Unconjugated
Gene	ATP23
Gene Alias	1110068E08Rik; 2410012H02Rik; atp23; ATP23 metallopeptidase and ATP synthase assembly factor homolog; Ku70 binding protein 3; Ku70-binding protein 3; KUB3; LOW QUALITY PROTEIN: mitochondrial inner membrane protease ATP23 homolog; mitochondrial inner membrane protease ATP23 homolog; XRCC6 binding protein 1; XRCC6-binding protein 1; Xrcc6bp1; zgc:162885
Host Species	Rabbit
Purification Method	Affinity Chromatography
Regulatory Status	RUO
Gene ID (Entrez)	299828, 68876
Content And Storage	-20°C, Avoid Freeze/Thaw Cycles
Form	Liquid

Applications	ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Concentration	0.2 mg/mL
Formulation	PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.	Q9CWQ3
Gene Symbols	ATP23
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-246 of human ATP23 (NP_1505921).
Quantity	100 μL
Primary or Secondary	Primary
Target Species	Mouse, Rat
Product Type	Antibody
Isotype	IgG

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Invitrogen™ XRCC6BP1 Polyclonal Antibody

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