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  5. Tocris Bioscience™ YIL 781 hydrochloride

Tocris Bioscience™ YIL 781 hydrochloride
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Product Code. 18796496
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25 mg
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18796496 25 mg 25mg
18789506 5 mg 5mg
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Product Code. 18796496 Supplier Tocris Bioscience™ Supplier No. 3959/25

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Description

Ghrelin receptor (GHS-R1a) antagonist

YIL 781 hydrochloride is a ghrelin receptor antagonist (GHS-R1a) (Ki = 17 nM). Displays no significant affinity for the motilin receptor (Ki = 6 μM). Blocks the effects of ghrelin on insulin secretion both in vivo and in vitro. Improves glucose homeostasis in vivo.
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Specifications

Chemical Name or Material 6-(4-Fluorophenoxy)-2-methyl-3-[[(3S)-1-(1-methylethyl)-3-piperidinyl]methyl]-4(3H)-quinazolinone hydrochloride
CAS 875258-85-8
Assay Percent Range >98%
Quantity 25 mg
Molecular Formula C24H28FN3O2.HCl
Formula Weight Observed MW: 445.96
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