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ZAP70 Antibody (ZAP70/528 + 2F3.2), HRP, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-47775H

Product Code. 18152198

  • € 678.00 / 0.10mL

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Description

Description

ZAP70 Monoclonal specifically detects ZAP70 in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

ZAP70
Monoclonal
HRP
PBS with No Preservative
ZAP70
Recombinant full-length human ZAP70 protein (ZAP70/528); Recombinant ZAP-70 protein including residues 1-254 and encompassing SH2 domains of human ZAP70 (2F3.2) (Uniprot: P43403)
0.1 mL
Primary
ZAP70 is a 70kDa protein tyrosine kinase found in T-cells and natural killer cells. Control of this protein translation is via the IgVH gene. ZAP70 protein is expressed in leukemic cells of approximately 25% of chronic lymphocytic leukemia (CLL) cases as well.Anti-ZAP70 expression is an excellent surrogate marker for the distinction between the Ig-mutated (anti-ZAP70 negative) and Ig-unmutated (anti-ZAP70 positive) CLL subtypes and can identify patient groups with divergent clinical courses. The anti-ZAP70 positive Ig-unmutated CLL cases have been shown to have a poorer prognosis.
Store at 4C in the dark.
IgG2a κ
Immunohistochemistry, Immunohistochemistry (Paraffin)
ZAP70/528 + 2F3.2
Immunohistochemistry, Immunohistochemistry-Paraffin
70 kDa zeta-associated protein, EC 2.7.10, EC 2.7.10.2, SRKFLJ17679, STDFLJ17670, Syk-related tyrosine kinase, tyrosine-protein kinase ZAP-70, TZK, ZAP-70, zeta-chain (TCR) associated protein kinase (70 kD), zeta-chain (TCR) associated protein kinase 70kDa, zeta-chain associated protein kinase, 70kD
Mouse
Protein A or G purified
Adaptive Immunity, Cell Biology, Immunology, Phospho Specific, Protein Kinase, Signal Transduction, Tyrosine Kinases
7535
Human
Purified
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