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ZBED1 Monoclonal Antibody (OTI2H3), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA505045
This item is not returnable.
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Description
ZBED1, also known as DREF, is the human homolog of the Drosophila protein DREF, a transcriptional regulatory factor required for expression of genes involved in DNA replication and cell proliferation. RNA interference (RNAi) experiments targeting ZBED1 RNA resulted in the inhibition of S phase entry and reduction of histone H1 mRNA in HeLa cells, suggesting that ZBED1 also plays a role in cell proliferation in human cells. At least 22 ribosomal proteins (RPs) possess ZBED1 binding sites in their promoters; anti-ZBED1 RNAi also resulted in decreased RP gene expression. Immunoprecipitation analyses have shown that ZBED1 self-associates in vivo via a carboxyl-terminal hATC domain, and this self-association is required for nuclear localization and DNA binding.Tekniske data
| ZBED1 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| O96006 | |
| ZBED1 | |
| Full length human recombit protein of human ZBED1 produced in HEK293T cell. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG2a |
| Flow Cytometry, Western Blot | |
| OTI2H3 | |
| Unconjugated | |
| ZBED1 | |
| ALTE, DREF, TRAMP, hDREF | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 9189 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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