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Invitrogen™ ZEB1 Recombinant Rabbit Monoclonal Antibody (24GB2265)

Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA557847

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Product Code. 30275529

  • € 198.00 / 20µL

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Description

Description

ZEB1 Recombinant Monoclonal Antibody for Flow, ICC/IF, Western Blot

ZEB1 (Zinc finger E-box-binding homeobox 1) acts as a transcriptional repressor. It inhibits interleukin-2 (IL-2) gene expression. ZEB1 enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and depending on the cell type. It represses E-cadherin promoters and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. ZEB1 also represses BCL6 transcription in the presence of the corepressor CTBP1. It postively regulates neuronal differentiation and represses RCOR1 transcription activation during neurogenesis. Mutations in the gene can result in corneal dystrophy, posterior polymorphous and corneal dystrophy, Fuchs endothelial 6.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

ZEB1
Recombinant Monoclonal
Unconjugated
ZEB1
[delta]EF1; 3110032K11Rik; AREB6; BZP; Delta EF1; delta-crystallin enhancer binding factor 1; deltaEF1; DELTA-EF1; FECD6; LOW QUALITY PROTEIN: zinc finger E-box-binding homeobox 1; MEB1; MGC133261; Negative regulator of IL2; Nil2; NIL2A; NIL-2A; NIL-2-A; NIL-2-A zinc finger protein; OTTHUMP00000019405; posterior polymorphous corneal dystrophy 3; PPCD3; RP11-472N13.4; Tcf18; TCF8; TCF-8; Transcription factor 8; transcription factor 8 (represses interleukin 2 expression); Tw; twirler; ZEB; Zeb1; Zfhep; Zfhx1a; Zfx1a; Zfx1ha; zinc finger E-box binding homeobox 1; zinc finger E-box-binding homeobox 1; Zinc finger homeobox protein 1a; zinc finger homeodomain enhancer-binding protein
Rabbit
Affinity chromatography
RUO
21417, 6935
-20°C
Liquid
Flow Cytometry, Western Blot, Immunocytochemistry
24GB2265
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
P37275, Q64318
ZEB1
A synthesized peptide derived from human AREB6 (aa 1-174).
20 μL
Primary
Human, Mouse
Antibody
IgG
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