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Invitrogen™ ZFYVE19 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA530856
This item is not returnable.
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Description
Recommended positive controls: K562. Predicted reactivity: Human (99%), Mouse (82%), Rat (84%), Bovine (84%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission.
Specifications
| ZFYVE19 | |
| Polyclonal | |
| Unconjugated | |
| ZFYVE19 | |
| 1500041L05Rik; abscission/NoCut checkpoint regulator; ANCHR; MLL partner containing FYVE domain; MPFYVE; Zfyve19; Zinc finger FYVE domain-containing protein 19; zinc finger FYVE-type containing 19; zinc finger, FYVE domain containing 19 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 84936 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot | |
| 1 mg/mL | |
| PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7 | |
| Q96K21 | |
| ZFYVE19 | |
| Recombinant protein encompassing a sequence within the center region of human ZFYVE19. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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