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Invitrogen™ ZNF174 Polyclonal Antibody
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Product Code. 16399344
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100 μL
Unit Size:
100µL
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16399344 100 μL 100µL
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Product Code. 16399344 Supplier Invitrogen™ Supplier No. PA582386

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Rabbit Polyclonal Antibody

Immunogen sequence: VSGPQEALSQ LRQLCRQWLQ PELHTKEQIL ELLVMEQFLT ILPPEIQARV RHRCPMSSKE IVTLVEDFHR ASKKPKQWVA VCMQGQKVLL EKTGSQLGEQ ELPDFQPQTP RRDLRESSPA EPSQAGAYDR LSPHHWEKSP LLQ Highest antigen sequence indentity to the following orthologs: Mouse - 79%, Rat - 79%.

ZNF174, also known as ZSCAN8 or AW-1, is a transcriptional repressor that belongs to the Krueppel C2H2-type zinc-finger protein family. It is expressed in a number of different tissues, including small intestine, prostate, colon, spleen, pancreas, skeletal muscle, brain, heart, kidney and thymus, but it is most predominantly found in adult ovary and testis. ZNF174 specifically acts to repress the promoter activities of PDGF-B and TGF beta1. ZNF174 localizes to the nucleus and contains three C2H2-type zinc fingers at the C-terminus and one SCAN domain near the N-terminus. SCAN domains are found in a number of zinc-finger proteins and are characterized by a conserved region of 84 residues. The SCAN domain seemingly regulates the association of proteins containing SCAN domains into noncovalent complexes and may also function as an underlying mechanism in selective oligomerization of these proteins.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZNF174
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ZNF174
Gene Accession No. Q15697
Gene Alias AW1; AW-1; zinc finger and SCAN domain-containing protein 8; Zinc finger protein 174; ZNF174; ZSCAN8
Gene Symbols ZNF174
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human ZNF174. Recombinant protein control fragment (Product #RP-102392).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7727
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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