missing translation for 'onlineSavingsMsg'
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Invitrogen™ ZNF598 Monoclonal Antibody (K92040_5C9), Invitrogen™
Description
Sequence of this protein is as follows: PRHSRRNEGV VGGEDYEEVD RYSRQGRVAR AGTRGAQQSR RGSWRYKREE EDREVAAAVR ASVAAQQQEE ARRSEDQEEG GRPKKEEAAA RGPEDPRGPR RSPRTQGEGP GPKETSTNGP VSQEAFSVTG
ZNF598 (E3 ubiquitin-protein ligase ZNF598) plays a key role in the ribosome quality control (RQC). RQC is a pathway that takes place when a ribosome has stalled during translation. It is required for ribosomes to terminally stall during translation of poly(A) sequences by mediating monoubiquitination of 40A ribosomal protein RPS10/eS10 and RPS3/uS3. Stalling precludes synthesis of a long poly-lysine tail and initiated the RQC pathway to degrade the potentially detrimental aberrant nascent polypeptide.
Specifications
Specifications
| Antigen | ZNF598 |
| Applications | Immunoprecipitation, Western Blot |
| Classification | Monoclonal |
| Clone | K92040_5C9 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide |
| Gene | ZNF598 |
| Gene Accession No. | Q86UK7 |
| Gene Alias | BC023040; C6orf149; E3 ubiquitin-protein ligase ZNF598; FLJ00086; ISD11; Ntrap; Zfp598; Zinc finger protein 598; ZNF598 |
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Product Title
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