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  6. Invitrogen™ ZNF598 Monoclonal Antibody (K92040_5C9), Invitrogen™

Invitrogen™ ZNF598 Monoclonal Antibody (K92040_5C9), Invitrogen™

Product Code. p-200088941
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Quantity:
50 μL
200 μL
Unit Size:
200µg
50µg
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Product Code. Quantity unitSize
30201363 200 μL 200µg
30207216 50 μL 50µg
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Product Code. 30201363 Supplier Invitrogen™ Supplier No. MA556099

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Description

Mouse Monoclonal Antibody

Sequence of this protein is as follows: PRHSRRNEGV VGGEDYEEVD RYSRQGRVAR AGTRGAQQSR RGSWRYKREE EDREVAAAVR ASVAAQQQEE ARRSEDQEEG GRPKKEEAAA RGPEDPRGPR RSPRTQGEGP GPKETSTNGP VSQEAFSVTG

ZNF598 (E3 ubiquitin-protein ligase ZNF598) plays a key role in the ribosome quality control (RQC). RQC is a pathway that takes place when a ribosome has stalled during translation. It is required for ribosomes to terminally stall during translation of poly(A) sequences by mediating monoubiquitination of 40A ribosomal protein RPS10/eS10 and RPS3/uS3. Stalling precludes synthesis of a long poly-lysine tail and initiated the RQC pathway to degrade the potentially detrimental aberrant nascent polypeptide.
TRUSTED_SUSTAINABILITY

Specifications

Antigen ZNF598
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone K92040_5C9
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Gene ZNF598
Gene Accession No. Q86UK7
Gene Alias BC023040; C6orf149; E3 ubiquitin-protein ligase ZNF598; FLJ00086; ISD11; Ntrap; Zfp598; Zinc finger protein 598; ZNF598
Gene Symbols ZNF598
Host Species Mouse
Immunogen Recombinant human ZNF598 (immunogen range is 291-420).
Purification Method Protein A
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 90850
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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