Benzenesulfonamides
Organic compounds that consist of a benzene ring substituted with a sulfonyl group that is subsequently bonded to an amino group; considered the amide of benzenesulfonic acid.
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Physical Form
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Quantity
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1
AKR1C3-IN-1, MedChemExpress
MedChemExpress AKR1C3-IN-1 is a potent, highly selective inhibitor of AKR1C3, with an IC50 of 13 nM.
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| Molecular Weight (g/mol) | 317.36 |
|---|---|
| Color | Light Yellow |
| Physical Form | Solid |
| Chemical Name or Material | AKR1C3-IN-1 |
| Grade | Research |
| SMILES | O=S(N1CC2=CC=CC=C2CC1)(C3=CC(C(O)=O)=CC=C3)=O |
| Percent Purity | 98.74% |
| CAS | 327092-81-9 |
| Solubility Information | DMSO : ≥ 100 mg/mL (315.10 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C16H15NO4S |
| Formula Weight | 317.36 |
2
FASN-IN-4, MedChemExpress
MedChemExpress FASN-IN-4 is a potent inhibitor of fatty acid synthase (FASN) with an IC50 of 10 nM (WO2012064642A1, compound 29). FASN-IN-4 also inhibits SARS-CoV-2 with an EC50 of 18.6 nM.
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3
Pazopanib, MedChemExpress
MedChemExpress Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ, c-Kit, FGFR1, and c-Fms with IC50s of 10, 30, 47, 84, 74, 140 and 146 nM, respectively.
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| Molecular Weight (g/mol) | 437.52 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | Pazopanib |
| Grade | Research |
| SMILES | O=S(C1=CC(NC2=NC=CC(N(C3=CC4=NN(C(C)=C4C=C3)C)C)=N2)=CC=C1C)(N)=O |
| For Use With (Application) | Cancer-Kinase/protease |
| Percent Purity | 98.0% |
| CAS | 444731-52-6 |
| Solubility Information | DMSO : 62.5 mg/mL (142.85 mM; Need ultrasonic) |
| Synonym | GW786034 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C21H23N7O2S |
| Formula Weight | 437.52 |
4
Sulfachloropyridazine, MedChemExpress
MedChemExpress Sulfachloropyridazine is a broad spectrum sulfonamide used against both Gram-positive and Gram-negative aerobic bacteria.
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5
Sulfacarbamide, MedChemExpress
MedChemExpress Sulfacarbamide is a blood sugar-lowering drug, also acting on the vegetative nervous system.
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6
2-Aminobenzenesulfonamide, MedChemExpress
MedChemExpress 2-Aminobenzenesulfonamide is a carbonic anhydrase IX inhibitor.
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7
VR23, MedChemExpress
MedChemExpress VR23 is a small molecule that potently inhibits the activities of trypsin-like proteasomes (IC50=1 nM), chymotrypsin-like proteasomes (IC50=50-100 nM), and caspase-like proteasomes (IC50=3 μM).
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| Molecular Weight (g/mol) | 477.88 |
|---|---|
| Color | Yellow |
| Physical Form | Solid |
| Chemical Name or Material | VR23 |
| Grade | Research |
| SMILES | O=S(N1CCN(C2=CC=NC3=CC(Cl)=CC=C23)CC1)(C4=CC=C([N+]([O-])=O)C=C4[N+]([O-])=O)=O |
| For Use With (Application) | Cancer-Kinase/protease |
| Percent Purity | 98.05% |
| CAS | 1624602-30-7 |
| Solubility Information | DMSO : 33.33 mg/mL (69.75 mM; Need ultrasonic) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C19H16ClN5O6S |
| Formula Weight | 477.88 |
8
ISCK03, MedChemExpress
MedChemExpress ISCK03 is a specific SCF/c-Kit inhibitor.
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| Molecular Weight (g/mol) | 355.45 |
|---|---|
| Color | Light Yellow |
| Physical Form | Powder |
| Chemical Name or Material | ISCK03 |
| Grade | Research |
| SMILES | O=S(C1=CC=C(C(C)(C)C)C=C1)(NC2=CC=C(N3C=CN=C3)C=C2)=O |
| For Use With (Application) | COVID-19-immunoregulation |
| Percent Purity | 99.27% |
| CAS | 945526-43-2 |
| Solubility Information | DMSO : ≥ 38 mg/mL (106.91 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C19H21N3O2S |
| Formula Weight | 355.45 |
9
PSB-12062, MedChemExpress
MedChemExpress PSB-12062 is a potent and selective P2X4 antagonist with an IC50 of 1.38 μM for human P2X4.
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| Molecular Weight (g/mol) | 337.39 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | PSB-12062 |
| Grade | Research |
| SMILES | O=S(N1C2=C(C=CC=C2)OC3=CC=CC=C13)(C4=CC=C(C)C=C4)=O |
| For Use With (Application) | Neuroscience-Neuromodulation |
| Percent Purity | 99.06% |
| CAS | 55476-47-6 |
| Solubility Information | DMSO : 25 mg/mL (74.10 mM; Need ultrasonic) |
| Health Hazard 1 | H302 |
| Synonym | N-(p-Methylphenylsulfonyl)phenoxazine |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C19H15NO3S |
| Formula Weight | 337.39 |
10
NMS-859, MedChemExpress
MedChemExpress NMS-859 is a potent, covalent VCP (p97) inhibitor, with IC50s of 0.37 and 0.36 μM for wild-type VCP in the presence of 60 μM and 1 mM ATP in cells, respectively.
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| Molecular Weight (g/mol) | 349.79 |
|---|---|
| Color | Gray |
| Physical Form | Solid |
| Chemical Name or Material | NMS-859 |
| Grade | Research |
| SMILES | O=S1(C2=CC=CC=C2C(NC3=CC(NC(CCl)=O)=CC=C3)=N1)=O |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 98.01% |
| CAS | 1449236-96-7 |
| Solubility Information | DMSO : ≥ 42 mg/mL (120.07 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C15H12ClN3O3S |
| Formula Weight | 349.79 |
11
Terutroban, MedChemExpress
MedChemExpress Terutroban is a thromboxane-prostaglandin receptor antagonist.
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| Molecular Weight (g/mol) | 407.91 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | Terutroban |
| Grade | Research |
| SMILES | O=C(O)CCC1=C2CC[C@@H](NS(=O)(C3=CC=C(Cl)C=C3)=O)CC2=CC=C1C |
| For Use With (Application) | COVID-19-immunoregulation |
| Percent Purity | 95.0% |
| CAS | 165538-40-9 |
| Solubility Information | DMSO : ≥ 22 mg/mL (53.93 mM) |
| Synonym | S-18886 |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C20H22ClNO4S |
| Formula Weight | 407.91 |
12
KI696, MedChemExpress
MedChemExpress KI696 is a high affinity probe that disrupts the Keap1/NRF2 interaction. KI696 is a potent and selective inhibitor of the KEAP1/NRF2 interaction.
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| Molecular Weight (g/mol) | 550.63 |
|---|---|
| Color | Off-White |
| Physical Form | Solid |
| Chemical Name or Material | KI696 |
| Grade | Research |
| SMILES | COC1=C(N2C)C(N=N2)=CC([C@H](C3=CC(CN(C[C@H]4C)S(=O)(C5=CC=CC=C5O4)=O)=C(C)C=C3)CC(O)=O)=C1 |
| For Use With (Application) | COVID-19-immunoregulation |
| Percent Purity | 98.0% |
| CAS | 1799974-70-1 |
| Solubility Information | DMSO : 50 mg/mL (90.81 mM; Need ultrasonic) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C28H30N4O6S |
| Formula Weight | 550.63 |
13
S0859, MedChemExpress
MedChemExpress S0859 is a selective, high-affinity generic Na+/HCO3- transporter (NBC) inhibitor. S0859 reversibly inhibits NBC-mediated intracellular pH (pHi) recovery (Ki=1.7 μM, full inhibition at approximately 30 μM).
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| Molecular Weight (g/mol) | 530.04 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | S0859 |
| Grade | Research |
| SMILES | O=C(N(CC1=CC=C(C2=CC=CC=C2S(=O)(NC#N)=O)C=C1)CC3=CC=C(C)C=C3)C4=CC=CC=C4Cl |
| For Use With (Application) | COVID-19-immunoregulation |
| Percent Purity | 98.0% |
| CAS | 1019331-10-2 |
| Solubility Information | DMSO : ≥ 100 mg/mL (188.67 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C29H24ClN3O3S |
| Formula Weight | 530.04 |
14
HJC0350, MedChemExpress
MedChemExpress HJC0350 is a potent and specific EPAC2 antagonist with an IC50 of 0.3 μM.
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| Molecular Weight (g/mol) | 277.38 |
|---|---|
| Color | Pink |
| Physical Form | Solid |
| Chemical Name or Material | HJC0350 |
| Grade | Research |
| SMILES | O=S(N1C(C)=CC(C)=C1)(C2=C(C)C=C(C)C=C2C)=O |
| For Use With (Application) | Cancer-programmed cell death |
| Percent Purity | 99.52% |
| CAS | 885434-70-8 |
| Solubility Information | DMSO : 33.33 mg/mL (120.16 mM; Need ultrasonic) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C15H19NO2S |
| Formula Weight | 277.38 |
15
AK-1, MedChemExpress
MedChemExpress AK-1 is a potent, specific and cell-permeable SIRT2 inhibitor, with an IC50 of 12.5 μM.
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| Molecular Weight (g/mol) | 403.45 |
|---|---|
| Color | White |
| Physical Form | Solid |
| Chemical Name or Material | AK-1 |
| Grade | Research |
| SMILES | O=C(NC1=CC=CC([N+]([O-])=O)=C1)C2=CC=CC(S(=O)(N3CCCCCC3)=O)=C2 |
| For Use With (Application) | Neuroscience-Neurodegeneration |
| Percent Purity | 99.8% |
| CAS | 330461-64-8 |
| Solubility Information | DMSO : ≥ 50 mg/mL (123.93 mM) |
| Purity Grade Notes | Research |
| Recommended Storage | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Shelf Life | Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month |
| Molecular Formula | C19H21N3O5S |
| Formula Weight | 403.45 |