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HPLC Columns and Cartridges

Pre-packed columns, cartridges, and guard columns for separation of biomolecules and organic/inorganic analytes; includes normal/reversed phase HPLC, UHPLC, LC-MS, HILIC, mixed-mode, ion exchange, ligand exchange, and affinity column formats.
HPLC Columns (9,573)
HPLC Guard Columns and Cartridges (651)
HPLC Guard Column Accessories (44)

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1
Promotions Available

Thermo Scientific™ Hypersil™ ODS C18 Columns

Use as a general purpose C18 phase for acidic and neutral analytes.

EDGE
Pore Size 120 Å
Carbon Load 10%
Stationary Phase C18
Temperature 60°C
Phase Reversed Phase
Endcapped Yes
Column Type Reversed Phase
pH 2 to 8
Surface Area 170 m²/g
USP Type L1
2
Promotions Available

Thermo Scientific™ Hypersil GOLD™ C18 Selectivity HPLC Columns
BIOPHARMA GREENER_CHOICE

Use these endcapped, ultrapure, silica-based columns to generate exceptional peak shape and resolution for HPLC and LC/MS analyses using generic gradients

EDGE
3
Promotions Available

Thermo Scientific™ Accucore™ C18 HPLC Columns
BIOPHARMA GREENER_CHOICE

Use this column, with its specially designed solid core, for a broad range of nonpolar analytes across multiple applications.

EDGE
Pore Size 80 Å
Particle Size 2.6 μm
Carbon Load 9%
Stationary Phase C18
Temperature 70°C
Phase Reversed Phase
Endcapped Yes
pH 1 to 11
Surface Area 130 m²/g
Particle Shape Solid Core
USP Type L1
4
Promotions Available

Thermo Scientific™ Hypersil™ BDS C18 Columns

Use as a robust, general-purpose column for a wide range of applications in QC/QA labs.

EDGE
Carbon Load 11%
Stationary Phase C18
Phase Reversed Phase
Endcapped Yes
Column Type Reversed Phase
Surface Area 170 m²/g
USP Type L1
5
Promotions Available

Thermo Scientific™ Hypersil GOLD™ aQ C18 Polar Endcapped HPLC Columns
BIOPHARMA GREENER_CHOICE

Retain and resolve polar analytes with highly aqueous mobile phases.

EDGE
Pore Size 175 Å
Carbon Load 12%
Temperature 60°C
Phase Reversed Phase
Endcapped Polar
pH 2 to 9
Surface Area 220 m²/g
USP Type L1
6
Promotions Available

Thermo Scientific™ POROS™ A 20 μm Protein A Affinity HPLC Columns

Thermo Scientific™ POROS™ Protein A is based on an immobilized recombinant Protein A functional group designed for high throughput purification of antibodies. The 20 micron particle size is used for high resolution and small scale preparative to semi-preparative separation of biomolecules.

EDGE
Particle Size 20 μm
Stationary Phase Recombinant Protein A
Binding Capacity 19 mg/mL
Product Line POROS
7
Promotions Available

Thermo Scientific™ EASY-Spray™ HPLC Columns
BIOPHARMA

Robust capillary flow HPLC columns for sensitive protein, peptide and mAbs separation using the stand alone or integrated easy to use design.

EDGE
Phase Reversed Phase
8
Promotions Available

Thermo Scientific™ Acclaim™ 120 C18 Columns

Use these high-efficiency reversed phase C18 columns for maximum resolution in a wide variety of applications.

EDGE
Pore Size 120 Å
Carbon Load 18%
Stationary Phase C18
Temperature 60°C
Endcapped Yes
Column Type Reversed Phase
pH 2 to 8
Surface Area 300 m²/g
USP Type L1
9
Promotions Available

Thermo Scientific™ Acclaim™ Trinity P2 HPLC Columns

Use these mixed-mode columns for separation of multivalent cations or anions and pharmaceuticals.

EDGE
Pore Size 300 Å
Solvents Compatible with most common HPLC organic solvents except for alcohols
Stationary Phase Spherical, Nanopolymer Hybrid Silica
Temperature 45°C
Phase HILIC and Ion Exchange
Endcapped Proprietary
Column Type Mixed Mode
Green Features FSC
Surface Area 100 m²/g
Max. Pressure 6000 psi (415 bar)
Particle Size 3 μm
Mobile Phase Compatibility 0 to 100% aqueous mobile phase
pH 2.5 to 7
Particle Shape Spherical silica
Product Line Acclaim
10
Promotions Available

Thermo Scientific™ Hypersil GOLD™ Amino HPLC Columns
BIOPHARMA

Achieve outstanding peak shape and sensitivity in weak anion exchange, reversed phase and normal phase modes with Hypersil GOLD Amino LC Columns.

EDGE
Pore Size 175 Å
Carbon Load 2%
Stationary Phase Amino (NH2)
Temperature 60°C
Phase Reversed Phase, Normal Phase, Ion Exchange, HILIC
Endcapped Yes
pH 2 to 8
Surface Area 220 m²/g
USP Type L8
11
Promotions Available

Thermo Scientific™ Hypersil™ Silica HPLC Columns

Use the efficient and selective Thermo Scientific™ Hypersil™ Silica LC Columns for normal phase chromatography of nonpolar and moderately polar organic compounds.

Pore Size 120 Å
Stationary Phase Silica
Temperature 60°C
Phase Normal Phase
Column Type Normal Phase
pH 2 to 8
Surface Area 170 m²/g
USP Type L3
12
Promotions Available

Thermo Scientific™ HyPURITY™ C18 HPLC Columns, 3μm Particle Size

Thermo ScientificTM HyPURITYTM C18 HPLC Columns are available in limited dimensions. Please contact Customer Service for more details.

13

Phenomenex™ Rezex™ RCM-Monosaccharide Ca+2 (8%), LC Column 300 x 7.8 mm

Rezex™ Ion Exclusion HPLC Columns for carbohydrate and organic acid separations.

14

Thermo Scientific™ POROS™ GoPure™ MabCapture A Pre-packed Column, 0.8 x 10 cm, 5 mL

Thermo Scientific™ POROS™ GoPure™ 0.8 cm pre-packed columns are intended for the screening of POROS affinity, ion exchange, and hydrophobic interaction chromatography (HIC) and hydrophobic interaction chromatography (HIC) resins or for small-scale purification.

15
Promotions Available

Thermo Scientific™ HyPURITY™ C18 Columns, 3μm Particle Size

High quality, highly pure silica columns

Pore Size 190 Å
Particle Size 3 μm
Carbon Load 13%
Stationary Phase C18
Phase Reversed Phase
Endcapped Yes
Packing Material Silica
Column Type Reversed Phase
pH 1 to 9
Surface Area 200 m²/g
USP Type L1