CAS RN 1360614-48-7
CAS RN 1360614-48-7
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Necrosulfonamide, MedChemExpress
MedChemExpress Necrosulfonamide is a necroptosis inhibitor acting by selectively targeting the mixed lineage kinase domain-like protein (MLKL). Necrosulfonamide prevents MLKL-RIP1-RIP3 necrosome complex from interacting with its downstream effectors. MLKL is a critical substrate of RIP3 during the induction of necrosis.
