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CAS RN 2137047-43-7

CAS RN 2137047-43-7

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1

Tocris Bioscience™ VU 6005649
GREENER_CHOICE

Positive allosteric modulators of mGlu7 and mGlu8 receptors. Also NK1 antagonist.

CAS 2137047-43-7
Purity 98%
Chemical Name or Material 3-(2,3-Difluoro-4-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
Recommended Storage Store at -20°C
Molecular Formula C16H12F5N3O
2

VU6005649, MedChemExpress

MedChemExpress VU6005649 is a CNS penetrant mGlu7/8 receptor agonist with EC50s of 0.65 μM and 2.6 μM for mGlu7 receptor and mGlu8 receptor, respectively.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 357.28
Color Yellow
Physical Form Solid
Chemical Name or Material VU6005649
Grade Research
SMILES CC1=NN2C(N=C(C)C=C2C(F)(F)F)=C1C3=CC=C(OC)C(F)=C3F
For Use With (Application) Neuroscience-Neuromodulation
Percent Purity 98.67%
CAS 2137047-43-7
Solubility Information DMSO : 50 mg/mL (139.95 mM; Need ultrasonic)
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C16H12F5N3O
Formula Weight 357.28