CAS RN 252935-94-7

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CHIR-98014, MedChemExpress

MedChemExpress CHIR-98014 is a potent, cell-permeable GSK-3 inhibitor with IC50s of 0.65 and 0.58 nM for GSK-3α and GSK-3β, respectively; it shows less potent activities against cdc2 and erk2.

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Molecular Weight (g/mol)	486.31
Color	Yellow
Physical Form	Solid
Chemical Name or Material	CHIR-98014
Grade	Research
SMILES	ClC1=CC(Cl)=CC=C1C2=NC(NCCNC3=CC=C([N+]([O-])=O)C(N)=N3)=NC=C2N4C=CN=C4
For Use With (Application)	Metabolism-sugar/lipid metabolism
Percent Purity	98.0%
CAS	252935-94-7
Solubility Information	DMSO : 12.5 mg/mL (25.70 mM; ultrasonic and warming and heat to 60°C)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₀H₁₇Cl₂N₉O₂
Formula Weight	486.31

CAS RN 252935-94-7

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