Crosslinking Reagents
Crosslinking Reagents
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Filtered Search Results
Thermo Scientific™ DSS (disuccinimidyl suberate), No-Weigh™ Format
Crosslink amines to amines with disuccinimidyl suberate composed of NHS-ester groups with a membrane-permeable, mid-length spacer for intracellular protein crosslinking.
Cleavable | No |
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PEGylated | No |
Thermo Scientific™ Sulfo-SMCC (sulfosuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate), No-Weigh™ Format
Crosslink amines to sulfhydryls with this mid-length, water-soluble crosslinker made of NHS-ester and maleimide groups at ends of a cyclohexane-containing, 8-atom spacer arm.
Shipping Condition | Ambient |
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Content And Storage | Upon receipt store desiccated at -20°C. |
Description | Sulfo-SMCC |
Cleavable | No |
Water Soluble | Yes |
Molecular Weight (g/mol) | 436.37 |
Solubility | Water |
Labeling Method | Chemical Labeling |
Crosslinker Type | Heterobifunctional |
Chemical Reactivity | Amine-Sulfhydryl |
Cell Permeability | No |
Format | Standard, Single-use, Premium-grade |
Product Type | Crosslinker |
Spacer | Short (<10 Å) |
Reactive Moiety | Maleimide, Sulfo-NHS Ester |
Spacer Arm Length | 8.3 Å |
PEGylated | No |
Thermo Scientific™ Pierce™ EDC, No-Weigh™ Format
Immobilize or conjugate proteins using 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide (CAS 25952-53-8), a water-soluble, carboxyl-to-amine crosslinker.
Shipping Condition | Wet Ice |
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Content And Storage | Upon receipt store desiccated at -20°C. |
Description | EDC |
Cleavable | No |
Water Soluble | Yes |
Form | Powder |
Molecular Weight (g/mol) | 191.7 |
Solubility | Water |
Labeling Method | Chemical Labeling |
Crosslinker Type | Heterobifunctional |
Chemical Reactivity | Amine-Carboxyl |
Cell Permeability | No |
Format | Standard, Single-use, Premium-grade |
Product Type | Crosslinker |
Spacer | Short (<10 Å) |
Reactive Moiety | Carbodiimide |
Spacer Arm Length | 0.0 Å |
PEGylated | No |
Thermo Scientific™ Pierce™ Premium Grade EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride)
Optimize applications where product integrity and risk minimization are paramount with this high-quality formulation of carbodiimide crosslinker.
Content And Storage | Upon receipt store desiccated at -20°C. |
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Description | EDC |
Cleavable | No |
Water Soluble | Yes |
Molecular Weight (g/mol) | 191.7 |
Solubility | Water |
Labeling Method | Chemical Labeling |
Crosslinker Type | Heterobifunctional |
Chemical Reactivity | Amine-Carboxyl |
Cell Permeability | No |
Format | Standard, Single-use, Premium-grade |
Product Type | Crosslinker |
Spacer | Short (<10 Å) |
Reactive Moiety | Carbodiimide |
Spacer Arm Length | 0.0 Å |
Product Line | Pierce™ |
PEGylated | No |
Thermo Scientific™ Sulfo-NHS (N-hydroxysulfosuccinimide), No-Weigh™ Format
Prepare amine-reactive sulfo-NHS-ester crosslinkers or enhance carbodiimide (EDC) conjugation for peptides or proteins using N-hydroxysulfosuccinimide, CAS 106627-54-7.
Molecular Weight (g/mol) | 217.13 |
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Solubility | Water |
PEGylated | No |
Thermo Scientific™ NHS-Azide
Activated azido compounds to derivatize proteins or amine surfaces for selective conjugation, detection or purification by phosphine-modified probes.
Thermo Scientific™ NHS (N-hydroxysuccinimide)
Prepare amine-reactive NHS-ester crosslinkers or enhance carbodiimide (EDC) conjugation for peptides or proteins using N-hydroxysuccinimide, CAS 6066-82-6.
Thermo Scientific™ Pierce™ Premium Grade Sulfo-NHS (N-hydroxysulfosuccinimide)
Optimize applications where product integrity and risk minimization are paramount with our highest quality formulation of this N-hydroxysuccinimide modification reagent.
Shipping Condition | Ambient |
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Content And Storage | Upon receipt store at 4°C. |
Description | Sulfo-NHS |
Cleavable | No |
Water Soluble | Yes |
Form | Powder |
Molecular Weight (g/mol) | 217.13 |
Solubility | Water |
Labeling Method | Chemical Labeling |
Crosslinker Type | Heterobifunctional |
Chemical Reactivity | Amine-Carboxyl |
Cell Permeability | No |
Format | Standard, Single-use, Premium-grade |
Product Type | Crosslinker |
Spacer | Short (<10 Å) |
Reactive Moiety | Carbodiimide |
Product Line | Pierce™ |
PEGylated | No |
Description | DSG |
---|---|
Cleavable | No |
Water Soluble | No |
Form | Powder |
Molecular Weight (g/mol) | 326.26 |
Solubility | DMF, DMSO |
Labeling Method | Chemical Labeling |
Crosslinker Type | Homobifunctional |
Chemical Reactivity | Amine-Amine |
Cell Permeability | Yes |
Format | Standard, Single-use |
Product Type | Crosslinker |
Spacer | Short (<10 Å) |
Reactive Moiety | NHS Ester |
Spacer Arm Length | 7.7 Å |
PEGylated | No |
Thermo Scientific™ BS3 (bis(sulfosuccinimidyl)suberate)
Crosslink amines to amines with BS3; composed of sulfo-NHS-ester groups separated by an 11.4A, water-soluble spacer arm that is useful for cell-surface protein crosslinking.
Cleavable | No |
---|---|
Molecular Weight (g/mol) | 572.43 |
Solubility | Water |
PEGylated | No |
Thermo Scientific™ BMPH (N-β-maleimidopropionic acid hydrazide)
Crosslink sulfhydryls to periodate-treated glycoprotein sugars with this short (8.1A) crosslinker containing maleimide and hydrazide groups.
Thermo Scientific™ SM(PEG)2 (PEGylated SMCC crosslinker)
Crosslink amines to sulfhydryls with these crosslinkers containing NHS-ester and maleimide groups at ends of water-soluble polyethylene glycol spacer arms (17.6 to 95.2A).
Shipping Condition | Ambient |
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Content And Storage | Upon receipt store desiccated at -20°C. |
Description | SM(PEG)2 |
Cleavable | No |
Water Soluble | Yes |
Form | Solid |
Molecular Weight (g/mol) | 425.39 |
Solubility | Water |
Labeling Method | Chemical Labeling |
Crosslinker Type | Heterobifunctional |
Chemical Reactivity | Amine-Sulfhydryl |
Cell Permeability | No |
Format | Standard, Single-use |
Product Type | Crosslinker |
Spacer | Medium (10 to 30 Å) |
Reactive Moiety | Maleimide, NHS Ester |
Spacer Arm Length | 17.6 Å |
Product Line | Pierce™ |
PEGylated | Yes |
Thermo Scientific™ SM(PEG)4 (PEGylated SMCC crosslinker)
Crosslink amines to sulfhydryls with these crosslinkers containing NHS-ester and maleimide groups at ends of water-soluble polyethylene glycol spacer arms (17.6 to 95.2A).
Shipping Condition | Ambient |
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Content And Storage | Upon receipt store desiccated at -20°C. |
Description | SM(PEG)4 |
Cleavable | No |
Water Soluble | Yes |
Form | Solid |
Molecular Weight (g/mol) | 513.5 |
Solubility | Water |
Labeling Method | Chemical Labeling |
Crosslinker Type | Heterobifunctional |
Chemical Reactivity | Amine-Sulfhydryl |
Cell Permeability | No |
Format | Standard |
Product Type | Crosslinker |
Spacer | Medium (10 to 30 Å) |
Reactive Moiety | Maleimide, NHS Ester |
Spacer Arm Length | 24.6 Å |
Product Line | Pierce™ |
PEGylated | Yes |
Thermo Scientific™ SM(PEG)6 (PEGylated, long-chain SMCC crosslinker)
Crosslink amines to sulfhydryls with these crosslinkers containing NHS-ester and maleimide groups at ends of water-soluble polyethylene glycol spacer arms (17.6 to 95.2A).
Thermo Scientific™ EZ-Link™ TFP Ester-PEG4-DBCO
An amine reactive heterobifunctional crosslinker which contains a dibenzylcyclooctyne (DBCO) group for copper-free click chemistry applications. The crosslinker can be used to label a variety of amine containing molecules such as proteins, biomolecules, or small molecules.
Shipping Condition | Wet Ice |
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Content And Storage | Upon receipt store desiccated at -20°C. |
Description | TFP Ester-PEG4-DBCO |
Cleavable | No |
Water Soluble | No |
Molecular Weight (g/mol) | 714.7 |
Solubility | DMF, DMSO |
Quantity | 10 x 1 mg |
Labeling Method | Chemical Labeling |
Crosslinker Type | Heterobifunctional |
Chemical Reactivity | Amine-Azide |
Cell Permeability | Not determined |
Format | Standard, Single-use |
Product Type | Crosslinker |
Spacer | Medium (10 to 30 Å) |
Reactive Moiety | TFP Ester, DBCO |
Spacer Arm Length | 17.9 Å |
Product Line | EZ-Link™ No-Weigh™ |
PEGylated | Yes |