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Tocris Bioscience™ DL-TBOA
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Product Code. 30001211
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 30001211

Brand: Tocris Bioscience™ 1223/50

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Description

Selective non-transportable inhibitor of EAATs

DL-TBOA is a competitive, non-transportable blocker of excitatory amino acid transporters (IC50 values are 6 μM, 6 μM and 70 μM, for EAAT2, EAAT3 and EAAT1 respectively). DL-TBOA also inhibits EAAT4 and EAAT5 (Ki values are 4.4 μM and 3.2 μM respectively). DL-TBOA displays high selectivity for EAATs over ionotropic and metabotropic glutamate receptors. DL-TBOA augments SN 38 (Cat. No. 2684) induced colorectal cancer cell death in drug-resistant cell lines. DL-TBOA enhances synaptic activity in the frog labyrinth.
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Chemical Identifiers

CAS 205309-81-5
Molecular Formula C11H13NO5

Specifications

Quantity 50 mg
Formula Weight 239.23
Purity >98%
Molecular Weight (g/mol) 239.227
Chemical Name or Material DL-TBOA
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