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Invitrogen™ ABL1 F317L Recombinant Human Protein

This ABL1 F317L Recombinant Human Protein (27-end) was expressed in insect cells.

Brand:  Invitrogen™ A33475

Additional Details : Weight : 0.10000kg

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Product Code. 15940403

  • € 467.00 / 10µg

Estimated Shipment: 09-01-2023
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Description

Description

  • This ABL1 F317L recombinant human protein (27–end) was expressed in insect cells
  • ABL1 cytoplasmic tyrosine kinase protooncogene encodes a cytoplasmic and nuclear kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response
  • Activity of ABL protein is negatively regulated by its SH3 domain and deletion of the SH3 domain turns ABL1 into an oncogene
  • Translocation and head-to-tail fusion of the BCR and ABL1 genes is present in many cases of chronic myelogeneous leukemia
  • The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDK1-mediated phosphorylation, suggesting a cell cycle function for ABL1
  • ABL1 F317L recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service
  • Validated for use with the Z'-LYTE™ assay
  • Available in multiple pack sizes for convenient use
Specifications

Specifications

NP_005148.2
10 µg
aa 27 - end
GST Tag
Dry Ice
Kinases & Inhibitors
Liquid
Human
146.3 kDa
ABL Kinase Family
Yes
Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Baculovirus
Recombinant, Active, Mutant
Kinase Assay
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