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Caveolin-1 (pY14) Mouse, Unlabeled, Clone: 56, BD
Mouse Monoclonal Antibody
€ 296.39 - € 421.58
Specifications
| Antigen | Caveolin-1 (pY14) |
|---|---|
| Clone | 56 |
| Concentration | 250μg/mL |
| Applications | Western Blot |
| Classification | Monoclonal |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15815889
|
BD Biosciences
611338 |
50 μg |
 € 298.00 € 296.39 / 1 set Save € 1.61 0.54% Off |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
|
15825889
|
BD Biosciences
611339 |
150 μg |
€ 423.00 € 421.58 / 1 set Save € 1.42 0.34% Off |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
Caveolin (VIP21) localizes to non-clathrin membrane invaginations (caveolae) on the inner surface of the plasma membrane. In addition, it is present in the trans-Golgi network (TGN) and in apically and basolaterally destined transport vesicles. Caveolin is a transmembrane adaptor molecule that recognizes GPI-linked proteins and interacts with downstream cytoplasmic signaling molecules, such as src-family tyrosine kinases and hetero-trimeric G proteins. Caveolin forms large lipid-binding oligomers, which are thought to play a role in caveolae formation. It may also function as a scaffolding protein, which organizes signaling molecules. This functional role is supported by the fact that caveolin interacts directly with inactive ras and G-protein α subunits. Phosphorylation of caveolin at Tyr-14, Ser-88, and other residues in v-src transformed cells leads to flattening, aggregation, and fusion of caveolae and caveolae-derived vesicles. Thus, caveolin is the principle protein of caveolae and may be involved in v-src mediated cellular transformation.
Host Species: Mouse
Clone: 56
Isotype: IgG1
Species Reactivity: Human
Immunogen: Phosphorylated Human Caveolin-1 (Y14) Peptide
Formula Weight [Chemical]: 21-24kDa
Flow Cytometry, Immunofluorescence, Immunohistochemistry, Intracellular Staining, Western Blotting
Specifications
| Caveolin-1 (pY14) | |
| 250μg/mL | |
| Monoclonal | |
| Mouse | |
| Cell Biology | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| IgG1 | |
| Affinity Purified |
| 56 | |
| Western Blot | |
| Unconjugated | |
| RUO | |
| Human, Mouse, Rat | |
| Phosphorylated Human Caveolin-1 (Y14) Peptide | |
| Primary | |
| Store undiluted at -20°C. |
For Research Use Only.
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