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  6. p150 [Glued] Mouse, Unlabeled, Clone: 12, BD
  7. 15856269

p150 [Glued] Mouse, Unlabeled, Clone: 12, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 612708

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Product Code. 15856269

  • € 251.00 / Each

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Description

Description

p150 [Glued] was identified as a polypeptide associated with cytoplasmic dynein,the minus-end-directed microtubule-based motor protein. p150 [Glued] is also a member of the oligomeric dynactin complex. Dynactin mediates dynein-driven vesicle motility, as well as lower eukaryote nuclear transport. p150 [Glued] bears significant homology to the product of the Glued gene in Drosophila. It has been shown in vitro to be a required activator of dynein-mediated transport along microtubules. The p150 [Glued] component of the dynactin complex binds to microtubules and the actin-like protein Centractin (Arp-1), another member of the dynactin complex. In the developing rat, p150 [Glued] is expressed at high levels in neural tissue. Microtubule binding assays with selected constructs of p150 [Glued] indicate that amino acids 39-150 are required for microtubule association.

Immunofluorescence, Western Blotting

TRUSTED_SUSTAINABILITY
Specifications

Specifications

p150 [Glued]
Monoclonal
250μg/mL
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Rat p150 [Glued] aa. 3-202
50 μg
Cell Biology
Canine, Human, Mouse, Rat
IgG1
In vitro Assay, Western Blot
12
Unconjugated
Mouse
Affinity Purified
RUO
Primary
Store undiluted at -20°C.
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