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Invitrogen™ ASPM Monoclonal Antibody (K52002_11G4), Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA555854
This item is not returnable.
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Description
Sequence of this protein is as follows: CKVPLSNENS QVPQSPEDWR KSEVSPRIPE CQGSKSPKAI FEELVEMKSN YYSFIKQNNP KFSAVQDISS HSHNKQPKRR PILSATVTKR KATCTRENQT EINKPKAKRC LNSAVGEHEK VINNQKEKED FHSYLPIIDP ILSKSKSYKN EVTPSSTTAS VARKRKSDGS MEDANVRVAI TEHTEVREIK RIHFSPSEPK TSAVKKTKNV TTPISKRISN REKLNLKKKT DLSIFRTPIS KTNKRTKPII AVAQSSLTFI KPLKTDIPRH PMPFAAKNMF YDERWKEKQE QGFTWWLNFI LTPDDFTVKT
This gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications
| ASPM | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide | |
| Q8IZT6 | |
| ASPM | |
| Recombinant human ASPM (immunogen range is 411-720). | |
| 50 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG2b |
| Immunohistochemistry (Paraffin) | |
| K52002_11G4 | |
| Unconjugated | |
| ASPM | |
| abnormal spindle microtubule assembly; Abnormal spindle protein homolog; Abnormal spindle-like microcephaly-associated protein; ASP; asp (abnormal spindle) homolog, microcephaly associated; Asp homolog; ASPM; Calmbp1; MCPH5 | |
| Mouse | |
| Protein A | |
| RUO | |
| 259266 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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