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  7. 17783614

Invitrogen™ Aurora C Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5122220

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Product Code. 17783614

  • € 208.00 / 20µL

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Description

Description

Aurora C Polyclonal Antibody for Western Blot, IHC (P)

AURKC (Aurora C) is a chromosomal passenger protein that forms complexes with AURKB (Aurora B) and inner centromere proteins, playing a role in organizing microtubules in relation to centrosome/spindle function during mitosis. It is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Studies on the temporal expression pattern and subcellular localization of Aurora kinases in mitotic cells suggest an association with mitotic structure. Aurora kinase functional influences span from G2 phase to cytokinesis and may be involved in key cell cycle events such as centrosome duplication, chromosome bi-orientation and segregation, cleavage furrow positioning, and ingression.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Aurora C
Polyclonal
Unconjugated
AURKC
AIE1; AIE2; AIK3; AIRK3; ARK3; ARK-3; AurC; AURKC; Aurora 3; aurora B; aurora kinase C; aurora/Ipl1/Eg2 protein 1; aurora/IPL1/EG2 protein 2; aurora/IPL1-related kinase 3; aurora-C; aurora-related kinase 3; epididymis secretory protein Li 90; HEL-S-90; IAK3; serine/threonine kinase 13 (aurora/IPL1-like); serine/threonine kinase 13 (aurora/IPL-like); serine/threonine-protein kinase 13; Serine/threonine-protein kinase aurora-C; SPGF5; STK13
Rabbit
Antigen affinity chromatography, Protein A
RUO
20871
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
O88445
AURKC
Recombinant protein Aurora Kinase C. The antigen corresponds to amino acid range 5-237 of the target protein.
20 μL
Primary
Mouse
Antibody
IgG
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