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Invitrogen™ AVEN Recombinant Rabbit Monoclonal Antibody (24GB6865)
Rabbit Recombinant Monoclonal Antibody
€ 146.00 - € 500.00
Specifications
| Antigen | AVEN |
|---|---|
| Clone | 24GB6865 |
| Content And Storage | -20°C |
| Applications | Flow Cytometry, Western Blot, Immunocytochemistry |
| Classification | Recombinant Monoclonal |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
30276363
|
Invitrogen™
MA556989 |
100 μL |
€ 500.00
100µL |
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|
30276578
|
Invitrogen™
MA556990 |
20 μL |
€ 146.00
20µL |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
AVEN Recombinant Monoclonal Antibody for Western Blot
Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Aven is a recently discovered protein that blocks apoptosis induced by Apaf-1 and caspase-9. It is thought that Aven functions by binding to Bcl-xL, an antiapoptotic member of the Bcl-2 family, and to Apaf-1, possibly interfering with the ability of Apaf-1 to self-associate, suggesting that Aven impedes Apaf-1-mediated caspase activation. Higher levels of Aven mRNA are seen in patients with acute leukemia than in control patients, suggesting that Aven may be useful as a prognostic indicator in leukemia patients.Specifications
| AVEN | |
| -20°C | |
| Recombinant Monoclonal | |
| Liquid | |
| IgG | |
| Human, Mouse, Rat | |
| AVEN | |
| 1700013A01Rik; 1700056A21Rik; apoptosis and caspase activation inhibitor; apoptosis, caspase activation inhibitor; AVEN; Cell death regulator Aven; mAven-L; mAven-S; PDCD12; programmed cell death 12 | |
| AVEN | |
| Primary | |
| Affinity chromatography |
| 24GB6865 | |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| Q9D9K3, Q9NQS1 | |
| 311299, 57099, 74268 | |
| A synthesized peptide derived from human AVEN (aa 113-126). | |
| Antibody |
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