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Invitrogen™ B7-H3 (CD276) Recombinant Rabbit Monoclonal Antibody (BLR026F)
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA544247
This item is not returnable.
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Description
Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.
CD276 is a member of the B7 family of co-stimulatory molecules also known as B7-H3. CD276 is a type I transmembrane protein that induces the proliferation of CD4+ and CD8+ T cells, enhances the generation of cytotoxic T cells and selectively stimulates the production of interferon gamma. Expression of CD276 can be induced on dendritic cells and monocytes by inflammatory cytokines, and is also widely expressed in peripheral tissues including the heart, kidney, testis and colon. In humans, CD276 exists as two isoforms which result from gene duplication and differential splicing. CD276 is reported to have therapeutic potential for the regulation of cell-mediated immune responses to cancer, particularly in conjunction with anti-angiogenic therapy.
Specifications
| B7-H3 (CD276) | |
| Recombinant Monoclonal | |
| 1 mg/mL | |
| BBS with 0.09% sodium azide; pH 8.2 | |
| Q5ZPR3 | |
| CD276 | |
| Recombinant protein representing the extracellular domain of human CD276 (residues 29-465). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
| Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry | |
| BLR026F | |
| Unconjugated | |
| CD276 | |
| 4Ig-B7-H3; 6030411F23Rik; AU016588; B7 homolog 3; B7h3; B7-H3; B7RP-2; CD276; CD276 antigen; CD276 molecule; CD276 molecule tv1; costimulatory molecule; PSEC0249; sB7 H3; sB7H3; sCD276; soluble B7 H3; soluble B7H3; soluble CD276; UNQ309/PRO352 | |
| Rabbit | |
| purified | |
| RUO | |
| 80381 | |
| 4°C | |
| Liquid |
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