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Thermo Scientific Chemicals Bafilomycin A1, 95%

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Product Code. 10295441 Supplier Thermo Scientific Chemicals Supplier No. 328120001
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Description

Bafilomycin A1, CAS # 88899-55-2, is an inhibitor of vacuolar ATPases from Streptomyces griseus that has antibacterial, antifungal, and antineoplastic activity. | CAS: 88899-55-2 | C35H58O9 | 622.84 g/mol

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Bafilomycin A1 is a specific potent inhibitor of vacuolar ATPases
  • It is a macrolide antibiotic, and shows fungicide activity

Application

  • Bafilomycin A1 has antibacterial, antifungal, and antineoplastic activity
  • It can be immunosuppressive
  • It can prevent maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes
  • It is a potent and selective inhibitor of vacuolar-type H+ ATPase (V-ATPase)
TRUSTED_SUSTAINABILITY

Specifications

Type Bafilomycin A1
Physical Form Powder/Solid
CAS 88899-55-2
Color White
Quantity 0.1 mg
Assay Percent Range 95%
Molecular Formula C35H58O9
MDL Number MFCD06795130
Solubility Information Solubility in water: practically insoluble. Other solubilities: soluble in methanol, ethanol, dmso
InChI Key XDHNQDDQEHDUTM-XRCNURIOSA-N
SMILES CC1CC(=CC=CC(C(OC(=O)C(=CC(=CC(C1O)C)C)OC)C(C)C(C(C)C2(CC(C(C(O2)C(C)C)C)O)O)O)OC)C
IUPAC Name (3Z,5E,7S,8R,9R,11Z,15R,16S)-16-[(2R,3S,4R)-4-[(2S,4S,5R,6S)-2,4-dihydroxy-5-methyl-6-propan-2-yloxan-2-yl]-3-hydroxypentan-2-yl]-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyl-1-oxacyclohexadeca-3,5,11,13-tetraen-2-one
Molecular Weight (g/mol) 622.84
PubChem CID 133268469
Formula Weight 622.8
Percent Purity 95%
Chemical Name or Material Bafilomycin A1, 95%
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Sicherheit und Handhabung

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Produktidentifikator
  • Bafilomycin A1
 Signalwort
  • Warning
 Gefahrenkategorie
  • Serious eye damage/eye irritation Category 2
  • Skin corrosion/irritation Category 2
  • Specific target organ toxicity Category 3
 Gefahrenhinweis
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
  • H315-Causes skin irritation.
 Sicherheitshinweis
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Sicherheitsdatenblatt (SDS)

RUO – Research Use Only

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