missing translation for 'onlineSavingsMsg'
Learn More
Learn More
CD105 (Endoglin) Mouse, anti-Human, FITC, Clone: 43A3, STEMCELL Technologies
Mouse Monoclonal Antibody
Brand: Stemcell Technologies 60039FI.1
This item is not returnable.
View return policy
Description
- The 43A3 antibody reacts with CD105 (endoglin), an ∼180 kDa cell surface glycoprotein which is a disulfide-bonded homodimer of ∼90 kDa type I transmembrane subunits
- CD105 is a component of the TGF-β receptor complex and is expressed by vascular endothelial smooth muscle cells, syncytiotrophoblasts of placenta and activated macrophages, and at relatively low levels by stromal fibroblasts
- Its expression is also observed in some types of tumors, and levels are up-regulated on the endothelium during angiogenesis
- CD105 has important roles in angiogenesis, cardiovascular development, and vascular remodeling, and the protein serves a regulatory role in cytoskeletal reorganization by modulating the sites of focal adhesion and cellular migration
- This antibody clone has been verified for labeling human mesenchymal cells grown in MesenCult™ Proliferation Kit (Human; Catalog #05411) and MesenCult™-XF Medium (Catalog #05420)
Specifications
| CD105 (Endoglin) | |
| Monoclonal | |
| FITC | |
| 25 Tests | |
| Human, Mouse | |
| Hematopoietic Stem and Progenitor Cells, Mesenchymal Stem and Progenitor Cells |
| Immunoprecipitation, Western Blot, Flow Cytometry | |
| 43A3 | |
| Mouse | |
| Primary | |
| IgG1 κ |
Product Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction