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CD105 (Endoglin) Mouse, anti-Human, FITC, Clone: 43A3, STEMCELL Technologies
Mouse Monoclonal Antibody
€ 166.05 - € 321.30
Specifications
| Antigen | CD105 (Endoglin) |
|---|---|
| Clone | 43A3 |
| Applications | Immunoprecipitation, Western Blot, Flow Cytometry |
| Classification | Monoclonal |
| Conjugate | FITC |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
17178711
|
Stemcell Technologies
60039FI.1 |
25 Tests |
€ 166.05
25 tests |
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|
17168711
|
Stemcell Technologies
60039FI |
100 Tests |
€ 321.30
100 tests |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
- The 43A3 antibody reacts with CD105 (endoglin), an ∼180 kDa cell surface glycoprotein which is a disulfide-bonded homodimer of ∼90 kDa type I transmembrane subunits
- CD105 is a component of the TGF-β receptor complex and is expressed by vascular endothelial smooth muscle cells, syncytiotrophoblasts of placenta and activated macrophages, and at relatively low levels by stromal fibroblasts
- Its expression is also observed in some types of tumors, and levels are up-regulated on the endothelium during angiogenesis
- CD105 has important roles in angiogenesis, cardiovascular development, and vascular remodeling, and the protein serves a regulatory role in cytoskeletal reorganization by modulating the sites of focal adhesion and cellular migration
- This antibody clone has been verified for labeling human mesenchymal cells grown in MesenCult™ Proliferation Kit (Human; Catalog #05411) and MesenCult™-XF Medium (Catalog #05420)
Specifications
| CD105 (Endoglin) | |
| Immunoprecipitation, Western Blot, Flow Cytometry | |
| FITC | |
| Human, Mouse | |
| Primary |
| 43A3 | |
| Monoclonal | |
| Mouse | |
| IgG1 κ |
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