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  6. CD19 Rat, anti-Mouse, Unconjugated, Clone: 1D3, STEMCELL Technologies

CD19 Rat, anti-Mouse, Unconjugated, Clone: 1D3, STEMCELL Technologies

Rat Monoclonal Antibody

POA - € 530.55

Specifications

Antigen CD19
Clone 1D3
Applications Immunohistochemistry, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Functional Assay
Classification Monoclonal
Conjugate Unconjugated
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
17129111
Encompass_Preferred
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Stemcell Technologies
60112.1 		100 μg This item is currently unavailable or has been discontinued.
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17119111
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Stemcell Technologies
60112 		500 μg
€ 530.55
500µg
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Description

Description

  • The 1D3 antibody reacts with mouse CD19, an ∼95 kDa type 1 transmembrane glycoprotein expressed on the surface of B cells throughout all stages of development, from early pre-B cells to plasma cells
  • Expression is down-regulated but persists in terminally differentiated plasma cells
  • CD19 is also found on follicular dendritic cells
  • By associating with CD21 and CD81, CD19 functions as a co-receptor for the B cell receptor and is involved in B cell activation and differentiation
  • Activation of CD19 is accompanied by phosphorylation of the cytoplasmic domain, which promotes binding to kinases and the induction of intracellular signaling cascades
  • Mutations in CD19 can result in severe immunodeficiency syndromes
  • Clone 1D3 recognizes the same epitope as clone 6D5 in cross-competition assays
Specifications

Specifications

CD19
Immunohistochemistry, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Functional Assay
Unconjugated
Mouse
Primary
1D3
Monoclonal
Rat
IgG2a κ
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