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CD226 (DNAM-1) Monoclonal Antibody (10E5), Functional Grade, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 16-2261-050
This item is not returnable.
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Description
This 10E5 MAb reacts with mouse CD226, which is also known as DNAX accessory molecule-1 (DNAM-1). CD226 is an adhesion molecule expressed primarily on T cells, including thymocytes. The highest levels of CD226 are found on naive CD8 T cells. Moreover, expression of CD226 is regulated differentially in CD4 T cells. Under certain culture conditions, CD226 can be upregulated in Th1 and downregulated in Th2 and Th0 cells. This cell surface receptor can also be detected on natural killer cells, some B cell subsets, monocytes, and platelets. Interaction with its ligands, the poliovirus receptor (CD155) and CD112, results in adhesion and cell signaling events that promote innate and adaptive immunity, including differentiation, survival, and cytotoxicity. The 10E5 MAb has been reported to inhibit antigen-specific T cell proliferation and IFN-gamma production in vivo.
CD226 (DNAM-1) Monoclonal antibody specifically detects CD226 (DNAM-1) in Mouse samples. It is validated for Flow Cytometry, Functional Assay
Specifications
| CD226 (DNAM-1) | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with no preservative; pH 7.2 | |
| Q8K4F0 | |
| Rat | |
| 50 mg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG2b κ |
| Flow Cytometry, Functional Assay | |
| 10E5 | |
| Functional Grade | |
| Cd226 | |
| adhesion glycoprotein; BC051526; Cd226; CD226 antigen; CD226 molecule; DNAM 1; DNAM1; DNAM-1; DNAX accessory molecule 1; DNAX accessory molecule-1; platelet and T cell activation antigen 1; platelet and T-cell activation antigen 1; Pta1; T lineage-specific activation antigen 1 antigen; TLiSA1 | |
| Affinity chromatography | |
| RUO | |
| 225825 | |
| 4° C | |
| Liquid |
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