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  6. Invitrogen™ CD45RB Monoclonal Antibody (16A), FITC
  7. 15334161

Invitrogen™ CD45RB Monoclonal Antibody (16A), FITC

Rat Monoclonal Antibody

Brand:  Invitrogen™ MA517885

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Product Code. 15334161

  • € 485.00 / 300µg

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Description

Description

CD45RB Monoclonal Antibody for Flow

CD45RB is a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains, but share identical transmembrane and cytoplasmic domains. CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45RB is expressed in microglia and inflammatory cells. In addition to involvement in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is involved in DNA fragmentation during apoptosis. CD45 is expressed on cells of the human hematopoietic lineage with the exception of mature red cells.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD45RB
Monoclonal
0.1 mg/mL
PBS with 4-5mg/mL BSA and 0.02% sodium azide
P06800
Ptprc
TH2 cell clones, final boost with TH2 clone D10 Fusion Partner: Ag8.653.
300 μg
Primary
Mouse
Antibody
IgG2a
Flow Cytometry
16A
FITC
Ptprc
B220; CD45; CD45 antigen; CD45R; GP180; LCA; L-CA; Leukocyte common antigen; loc; LY5; Ly-5; Lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; PTPRC; Receptor-type tyrosine-protein phosphatase C; T200; T200 glycoprotein; T200 leukocyte common antigen
Rat
Protein G
RUO
19264
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Liquid
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