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Invitrogen™ CD45RB Monoclonal Antibody (16A), FITC

Rat Monoclonal Antibody

€ 228.00 - € 485.00

Specifications

Antigen CD45RB
Clone 16A
Concentration 0.1 mg/mL
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Applications Flow Cytometry
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15324161
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Invitrogen™
MA517884
100 μg
€ 228.00
100µg
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15334161
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Invitrogen™
MA517885
300 μg
€ 485.00
300µg
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Description

Description

CD45RB Monoclonal Antibody for Flow

CD45RB is a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains, but share identical transmembrane and cytoplasmic domains. CD45 isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45RB is expressed in microglia and inflammatory cells. In addition to involvement in immunoreceptor signaling, CD45 is important in promoting cell survival by modulating integrin-mediated signal transduction pathway and is involved in DNA fragmentation during apoptosis. CD45 is expressed on cells of the human hematopoietic lineage with the exception of mature red cells.
Specifications

Specifications

CD45RB
0.1 mg/mL
Flow Cytometry
FITC
Rat
RUO
PBS with 4-5mg/mL BSA and 0.02% sodium azide
P06800
19264
TH2 cell clones, final boost with TH2 clone D10 Fusion Partner: Ag8.653.
Antibody
16A
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Monoclonal
Liquid
IgG2a
Mouse
Ptprc
B220; CD45; CD45 antigen; CD45R; GP180; LCA; L-CA; Leukocyte common antigen; loc; LY5; Ly-5; Lymphocyte antigen 5; lymphocyte common antigen; Lyt-4; membrane tyrosine phosphatase; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; PTPRC; Receptor-type tyrosine-protein phosphatase C; T200; T200 glycoprotein; T200 leukocyte common antigen
Ptprc
Primary
Protein G
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