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Chromogranin A Mouse, Clone: LK2H10 + PHE5 + CGA/414, Novus Biologicals™
Mouse Monoclonal Antibody
Brand: Novus Biologicals NBP2-34240-0.1MG
This item is not returnable.
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Description
Chromogranin A Monoclonal specifically detects Chromogranin A in Human, Mouse, Rat, Porcine, Monkey samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
Specifications
| Chromogranin A | |
| Monoclonal | |
| Unconjugated | |
| PBS with 0.05% BSA. with 0.05% Sodium Azide | |
| betagranin (N-terminal fragment of chromogranin A), CGA, chromogranin A (parathyroid secretory protein 1), chromogranin-A, parathyroid secretory protein 1, Pituitary secretory protein I, SP-I | |
| Mouse | |
| 72 kDa | |
| 0.1 mg | |
| Apoptosis, Cancer, Neuronal Cell Markers | |
| 1113 | |
| Human, Mouse, Rat, Pig, Primate | |
| Purified |
| Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin) | |
| LK2H10 + PHE5 + CGA/414 | |
| Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml | |
| P10645 | |
| CHGA | |
| Human pheochromocytoma (LK2H10 & PHE5) & recombinant human chromogranin A protein (CGA414) | |
| Protein A purified | |
| RUO | |
| Primary | |
| Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin. | |
| Store at 4C. | |
| IgG |
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