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CSE1L Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 22219-1-AP-20UL

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Product Code. 16851755

  • € 145.00 / 20µL

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Description

Description

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation.
Specifications

Specifications

CSE1L
Polyclonal
Unconjugated
CSE1L
CAS, CSE1, CSE1L, Exp2, Exportin 2, Importin alpha re exporter, XPO2
Rabbit
Antigen Affinity Chromatography
RUO
110750, 1434
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation
0.19 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P55060, Q9ERK4
Cse1l
CSE1L Fusion Protein Ag17556
20 μL
Primary
Human, Mouse
Antibody
IgG
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