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Cytokeratin 10 Antibody (DE-K10), Novus Biologicals™

Mouse Monoclonal Antibody

€ 295.00 - € 522.00

Specifications

Antigen Cytokeratin 10
Clone DE-K10
Dilution Flow Cytometry 0.5-1ug/million cells in 0.1ml, Immunohistochemistry-Paraffin 0.1-0.2ug/ml, Immunofluorescence 0.5-1ug/ml
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Classification Monoclonal
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
18118407
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Novus Biologicals
NBP2-47650-0.02MG
0.02 mg
€ 295.00
0.02mg
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18075734
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Novus Biologicals
NBP2-47650-0.1MG
0.1 mg
€ 522.00
0.10mg
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Description

Description

Cytokeratin 10 Monoclonal specifically detects Cytokeratin 10 in Human, Canine, Feline samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
Specifications

Specifications

Cytokeratin 10
Flow Cytometry 0.5-1ug/million cells in 0.1ml, Immunohistochemistry-Paraffin 0.1-0.2ug/ml, Immunofluorescence 0.5-1ug/ml
Monoclonal
Purified
RUO
Human, Canine, Feline
BCIE, BIE, CK10, CK-10, cytokeratin 10, Cytokeratin-10, EHK, K10keratosis palmaris et plantaris, keratin 10, Keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris), keratin, type I cytoskeletal 10, keratin-10, KPP
KRT10
IgG1 κ
Protein A or G purified
This MAb recognizes a protein of 56.5kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.
DE-K10
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Unconjugated
Mouse
Cytoskeleton Markers
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
3858
Cytoskeletal preparation extracted from human ectocervical epithelium
Primary
Store at 4C.
56.5 kDa
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