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  5. Tocris Bioscience™ Gabexate mesylate

Tocris Bioscience™ Gabexate mesylate
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Product Code. 18083932
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18083932

Brand: Tocris Bioscience™ 1798/10

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Description

Serine protease inhibitor; inhibits thrombin, trypsin, kallikrein and plasmin

Gabexate mesylate is a serine protease inhibitor; Gabexate mesylate inhibits trypsin, plasmin, plasma kallikrein and thrombin (IC50 values are 9.4, 30, 41 and 110 μM respectively). Antithrombotic in vitro and in vivo. Gabexate mesylate also inhibits LPS-induced TNF-α production, probably by inhibiting NF-κB and AP-1 activation. Gabexate mesylate attenuates allergen-induced airway inflammation and eosinophils infiltration in the lung of asthma murine model.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 56974-61-9
Molecular Formula C17H27N3O7S

Specifications

Quantity 10 mg
Formula Weight 417.48
Purity >98%
Molecular Weight (g/mol) 417.48
Chemical Name or Material Gabexate mesylate
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