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GRB2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 10254-2-AP-20UL
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Description
GRB 2 protein contains one SH2 domain flanked on both sides by an SH3 domain. In response to EGF, GRB 2 binds, through its SH3 domains, to the guanine nucleotide exchange factor, Sos. The GRB 2 - Sos complex then binds the EGF receptor. These interactions play a critical role in the activation of the p21 ras signaling pathway.Specifications
| GRB2 | |
| Polyclonal | |
| Unconjugated | |
| GRB2 | |
| Adapter protein GRB2, ASH, EGFRBP GRB2, GRB2, Grb3 3, MST084, MSTP084, Protein Ash, SH2/SH3 adapter GRB2 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 14784, 2885, 81504 | |
| -20°C | |
| Liquid |
| Immunofluorescence, Immunohistochemistry (Paraffin), Immunocytochemistry, Western Blot | |
| 0.33 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| P62993, P62994, Q60631 | |
| GRB2 | |
| GRB2 Fusion Protein Ag0395 | |
| 20 μL | |
| Primary | |
| Rat, Human, Mouse | |
| Antibody | |
| IgG |
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