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Invitrogen™ Human MAP2K4 (MEK4), GST Tag Recombinant Protein
Human MAP2K4 (MEK4), GST Tag Recombinant Protein
Brand: Invitrogen™ A30976
Additional Details : Weight : 0.10000kg
Description
- This MAP2K4 (MEK4) recombinant human protein (full length) was expressed in insect cells
- MAP2K4 (MEK4) serine/threonine kinase (mitogen-activated protein kinase kinase 4) is a dual specificity kinase
- It is a member of the STE7 family that phosphorylates and activates JNK1, and -2, as well as p38
- MAP2K4 preferentially phosphorylates the tyrosine residue of JNKs
- MAP2K4 mediates a variety of physiological and pathophysiological processes such as responses to cellular stresses and inflammatory cytokines
- MAP2K4 is important for carcinogenesis; a loss-off-function mutation in MAP2K4 was found in lung and pancreatic tumors
- Conversely, a pro-oncogenic role was also found for MAP2K4
- MAP2K4 (MEK4) recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service
- Validated for use with the LanthaScreen™ Eu Kinase Binding assay
- Available in multiple pack sizes for convenient use
Specifications
| NP_003001 | |
| 70.6 kDa | |
| MAP Kinases | |
| Human | |
| GST Tag | |
| Dry Ice | |
| Kinases & Inhibitors | |
| Liquid |
| Kinase Assay | |
| 10 mg | |
| Full Length | |
| Recombinant | |
| Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. | |
| Baculovirus | |
| Full Length, Recombinant, Active |