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MFN1 Mouse anti-Human, Clone: 3F11C11, Proteintech
Mouse Monoclonal Antibody
Brand: Proteintech 66776-1-IG-150UL
This item is not returnable.
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Description
Mitofusin 1 (MFN1) and the related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. MFN1 and MFN2 form homotypic and heterotypic complexes and coordinately regulate mitochondrial fusion and are essential for embryonic development. When ectopically expressed, MFN1 inhibits the apoptosis-associated amino-terminal conformation change in the apoptotic protein Bax but not its mitochondrial translocation, indicating that MFN1 is involved in the regulating the activation of Bax on the outer mitochondrial membrane.Specifications
| MFN1 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| Q8IWA4 | |
| MFN1 | |
| MFN1 Fusion Protein Ag4890 | |
| 150 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG2a |
| Immunohistochemistry (Paraffin), Western Blot | |
| 3F11C11 | |
| Unconjugated | |
| MFN1 | |
| DKFZp762F247, FLJ20693, Fzo homolog, hfzo1, hfzo2, MFN1, mitofusin 1, Transmembrane GTPase MFN1 | |
| Mouse | |
| Protein A | |
| RUO | |
| 55669 | |
| -20°C | |
| Liquid |
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