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MFN1 Mouse anti-Human, Clone: 3F11C11, Proteintech

Mouse Monoclonal Antibody

€ 145.00 - € 410.00

Specifications

Antigen MFN1
Clone 3F11C11
Concentration 1 mg/mL
Applications Western Blot, Immunohistochemistry (Paraffin)
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16848965
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Proteintech
66776-1-IG-20UL
20 μL
€ 145.00
20µL
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16838965
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Proteintech
66776-1-IG-150UL
150 μL
€ 410.00
150µL
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Description

Description

Mitofusin 1 (MFN1) and the related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. MFN1 and MFN2 form homotypic and heterotypic complexes and coordinately regulate mitochondrial fusion and are essential for embryonic development. When ectopically expressed, MFN1 inhibits the apoptosis-associated amino-terminal conformation change in the apoptotic protein Bax but not its mitochondrial translocation, indicating that MFN1 is involved in the regulating the activation of Bax on the outer mitochondrial membrane.
Specifications

Specifications

MFN1
1 mg/mL
Monoclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
DKFZp762F247, FLJ20693, Fzo homolog, hfzo1, hfzo2, MFN1, mitofusin 1, Transmembrane GTPase MFN1
MFN1
IgG2a
Protein A
Antibody
3F11C11
Western Blot, Immunohistochemistry (Paraffin)
Unconjugated
Mouse
Human
Q8IWA4
55669
MFN1 Fusion Protein Ag4890
Primary
-20°C
MFN1
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Documents

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