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NLRP2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 15182-1-AP-20UL
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Description
NALP2 belongs to a family of cytoplasmic proteins that have been implicated in cell responses to apoptotic and inflammatory stimuli. Unlike the prototypical NALP protein NALP1, NALP2 only contains a NACHT domain, leucine rich repeat (LRR), and pyrin-containing domain (PYD). This protein interacts with the adapter protein ASC in addition to CARD8 and caspase-1 to form an inflammasome with high proIL-1-b-processing activity and is thought to function as a modulator of NF-kappa-B and procaspase-1 activation in macrophages. It has also been suggested that NALP2, in addition to other NALP family members, can act as innate sensors of pathogens in a manner similar to the toll-like receptors (TLRs). At least two alternatively spliced transcript variants encoding distinct isoforms have been found for NALP2.Specifications
| NLRP2 | |
| Polyclonal | |
| Unconjugated | |
| NLRP2 | |
| CLR19.9, NALP2, NBS1, NLRP2, PAN1, PYPAF2 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 232827, 55655 | |
| -20°C | |
| Liquid |
| Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation | |
| 0.21 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q9NX02 | |
| NLRP2 | |
| NLRP2 Fusion Protein Ag7167 | |
| 20 μL | |
| Primary | |
| Mouse, Human | |
| Antibody | |
| IgG |
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