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NLRP2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

€ 145.00 - € 410.00

Specifications

Antigen NLRP2
Concentration 0.21 mg/mL
Applications Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16814254
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Proteintech
15182-1-AP-20UL
20 μL
€ 145.00
20µL
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16804254
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Proteintech
15182-1-AP-150UL
150 μL
€ 410.00
150µL
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Description

Description

NALP2 belongs to a family of cytoplasmic proteins that have been implicated in cell responses to apoptotic and inflammatory stimuli. Unlike the prototypical NALP protein NALP1, NALP2 only contains a NACHT domain, leucine rich repeat (LRR), and pyrin-containing domain (PYD). This protein interacts with the adapter protein ASC in addition to CARD8 and caspase-1 to form an inflammasome with high proIL-1-b-processing activity and is thought to function as a modulator of NF-kappa-B and procaspase-1 activation in macrophages. It has also been suggested that NALP2, in addition to other NALP family members, can act as innate sensors of pathogens in a manner similar to the toll-like receptors (TLRs). At least two alternatively spliced transcript variants encoding distinct isoforms have been found for NALP2.
Specifications

Specifications

NLRP2
Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation
Unconjugated
Rabbit
Mouse, Human
Q9NX02
232827, 55655
NLRP2 Fusion Protein Ag7167
Primary
-20°C
NLRP2
0.21 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
CLR19.9, NALP2, NBS1, NLRP2, PAN1, PYPAF2
NLRP2
IgG
Antigen Affinity Chromatography
Antibody
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Documents

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