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SLA/LP Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
€ 145.00 - € 410.00
Specifications
| Antigen | SLA/LP |
|---|---|
| Concentration | 0.15 mg/mL |
| Applications | Western Blot, Immunoprecipitation |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
16818713
|
Proteintech
11551-1-AP-20UL |
20 μL |
€ 145.00
20µL |
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|
16808713
|
Proteintech
11551-1-AP-150UL |
150 μL |
€ 410.00
150µL |
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Description
SLAP also known as Src-like-adapter protein 1 is a 276 amino acid containing adapter protein, functioning as a negative regulator of T-cell receptor (TCR) signaling. SLAP belonging to the SRC family of cytoplasmic tyrosine kinases contains a SH2 domain and a SH3 domain. This cytoplasmic protein colocalizes with endosomes and is known to inhibit T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. It acts as a negative regulator of positive selection and mitosis of T-cells. SLAP may act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins. Expression of SLAP is weak in heart, adult brain, placenta, liver, skeletal muscle, kidney and pancreas but is high in lung and fetal brain.Specifications
| SLA/LP | |
| Western Blot, Immunoprecipitation | |
| Unconjugated | |
| Rabbit | |
| Rat, Human, Mouse | |
| Q6P6M7, Q9HD40 | |
| 211006, 51091, 679383 | |
| SLA/LP Fusion Protein Ag2097 | |
| Primary | |
| -20°C | |
| SEPSECS |
| 0.15 mg/mL | |
| Polyclonal | |
| Liquid | |
| RUO | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| Liver pancreas antigen, LP, Sec synthase, Selenocysteine synthase, Sep tRNA:Sec tRNA synthase, SEPSECS, SLA, SLA p35, SLA/LP, SLA/LP autoantigen, Soluble liver antigen, TRNP48 | |
| SEPSECS | |
| IgG | |
| Antigen Affinity Chromatography | |
| Antibody |
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