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TACC3 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 25697-1-AP-150UL
This item is not returnable.
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Description
This antibody works well in WB, IHC and IF application.
TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 4,8, and 10. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC. It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to interact with centrosomes and microtubules in a similar manner.Specifications
| TACC3 | |
| Polyclonal | |
| Unconjugated | |
| TACC3 | |
| ERIC 1, ERIC1, TACC3 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 10460 | |
| -20°C | |
| Liquid |
| Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
| 0.27 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| Q9Y6A5 | |
| TACC3 | |
| TACC3 Fusion Protein Ag22516 | |
| 150 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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