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TACC3 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

€ 145.00 - € 410.00

Specifications

Antigen TACC3
Concentration 0.27 mg/mL
Applications Immunohistochemistry (Paraffin), Western Blot, Immunofluorescence, Immunocytochemistry
Classification Polyclonal
Conjugate Unconjugated
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
16824265
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Proteintech
25697-1-AP-20UL
20 μL
€ 145.00
20µL
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16814265
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Proteintech
25697-1-AP-150UL
150 μL
€ 410.00
150µL
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Description

Description

This antibody works well in WB, IHC and IF application.

TACC1 is located on 8p11 chromosomal region that is amplified in approximately 15% of all breast tumor samples. The short arm of chromosome 8 also contains FGFR1 whose expression is enhanced in most breast cancer tumors. TACC family members, TACC1, TACC2, and TACC3, map very closely to the corresponding FGFR1, FGFR2, FGFR3 genes on chromosomes 4,8, and 10. Subsequently, since they are phylogenetically related, it is proposed that TACC and FGFR have similar roles in cell growth and differentiation. Also, TACC1 contains a conserved C-terminal region as in the Drosophila homolog, D-TACC. It has been shown that D-TACC is necessary for normal spindle function, and the mammalian TACC proteins appears to interact with centrosomes and microtubules in a similar manner.
Specifications

Specifications

TACC3
Immunohistochemistry (Paraffin), Western Blot, Immunofluorescence, Immunocytochemistry
Unconjugated
Rabbit
Human
Q9Y6A5
10460
TACC3 Fusion Protein Ag22516
Primary
-20°C
TACC3
0.27 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
ERIC 1, ERIC1, TACC3
TACC3
IgG
Antigen Affinity Chromatography
Antibody
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