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TIMP-3 Antibody, Novus Biologicals™

Rabbit Polyclonal Antibody

Brand:  Novus Biologicals NBP2-29478-20ug

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Product Code. 18451862

  • € 256.00 / 20µg

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Description

Description

TIMP-3 Polyclonal specifically detects TIMP-3 in Human, Mouse, Rat, Bovine, Canine, Equine samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

TIMP-3
Polyclonal
Unconjugated
PBS with 0.05% BSA. with 0.05% Sodium Azide
HSMRK222, K222, K222TA2, metalloproteinase inhibitor 3, MIG-5 protein, Protein MIG-5, pseudoinflammatory), SFD, TIMP metallopeptidase inhibitor 3, TIMP-3, tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, Tissue inhibitor of metalloproteinases 3
Rabbit
30 kDa
20 ug
Angiogenesis, Apoptosis, Cancer, Hypoxia, Metastasis, Vision
7078
Human, Bovine, Canine, Equine, Sheep
Purified
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
0.2 mg/ml
Flow Cytometry 0.5-1ug/million cells, Immunohistochemistry 1-2ug/ml, Immunocytochemistry/Immunofluorescence 1-2ug/mlimmunohistochemistry 1-2ug/ml, Immunohistochemistry-Paraffin
P35625
TIMP3
TIMP-3 (aa175-211) (Uniprot: P35625)
Protein A purified
RUO
Primary
TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2, and TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM). An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP s inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes.
Store at 4C.
IgG
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