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TIMP-3 Antibody, Novus Biologicals™

Rabbit Polyclonal Antibody

€ 256.00 - € 517.00

Specifications

Antigen TIMP-3
Concentration 0.2 mg/ml
Dilution Flow Cytometry 0.5-1ug/million cells, Immunohistochemistry 1-2ug/ml, Immunocytochemistry/Immunofluorescence 1-2ug/mlimmunohistochemistry 1-2ug/ml, Immunohistochemistry-Paraffin
Applications Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Classification Polyclonal
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
18451862
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Novus Biologicals
NBP2-29478-20ug
20 ug
€ 256.00
20µg
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18143183
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Novus Biologicals
NBP2-29478
0.1 mg
€ 517.00
0.10mg
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Description

Description

TIMP-3 Polyclonal specifically detects TIMP-3 in Human, Mouse, Rat, Bovine, Canine, Equine samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.
Specifications

Specifications

TIMP-3
Flow Cytometry 0.5-1ug/million cells, Immunohistochemistry 1-2ug/ml, Immunocytochemistry/Immunofluorescence 1-2ug/mlimmunohistochemistry 1-2ug/ml, Immunohistochemistry-Paraffin
Polyclonal
Purified
RUO
Human, Bovine, Canine, Equine, Sheep
P35625
7078
TIMP-3 (aa175-211) (Uniprot: P35625)
Primary
Store at 4C.
30 kDa
0.2 mg/ml
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Unconjugated
Rabbit
Angiogenesis, Apoptosis, Cancer, Hypoxia, Metastasis, Vision
PBS with 0.05% BSA. with 0.05% Sodium Azide
HSMRK222, K222, K222TA2, metalloproteinase inhibitor 3, MIG-5 protein, Protein MIG-5, pseudoinflammatory), SFD, TIMP metallopeptidase inhibitor 3, TIMP-3, tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, Tissue inhibitor of metalloproteinases 3
TIMP3
IgG
Protein A purified
TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2, and TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM). An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP s inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes.
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