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Invitrogen™ TOP3A Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
€ 180.00 - € 453.00
Specifications
| Antigen | TOP3A |
|---|---|
| Concentration | 0.5 mg/mL |
| Applications | Immunohistochemistry (Paraffin) |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
17772934
|
Invitrogen™
PA5121539 |
20 μL |
€ 180.00
20µL |
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|
17762934
|
Invitrogen™
PA5121538 |
100 μL |
€ 453.00
100µL |
Please sign in to purchase this item. Need a web account? Register with us today! | |||||
Description
DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA by transiently breaking and rejoining DNA strands. Although DNA topoisomerase I (Topo I) and Topo II relax both positive and negative supercoils, Topo III relaxes only negative supercoils. Topo IIIalpha exists as a long and a short isoform, which are produced by alternative splicing. Topo IIIalpha, which localizes to the nucleolus, is constitutively expressed and remains at high levels throughout the cell cycle in HL-60 cells. Topo IIIbeta exists as three isoforms,beta-1,beta -2 and beta-3, also produced by alternative splicing. Topo IIIbeta-1 is expressed in testis, heart, and skeletal muscle, whereas Topo IIIbeta-2 is expressed in thymus, kidney and pancreas.Specifications
| TOP3A | |
| Immunohistochemistry (Paraffin) | |
| Unconjugated | |
| Rabbit | |
| Human | |
| Q13472 | |
| 7156 | |
| Lys35-Ser179 (Accession Q13472), with N-terminal His Tag. | |
| Primary | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Top3a |
| 0.5 mg/mL | |
| Polyclonal | |
| Liquid | |
| RUO | |
| PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4 | |
| DNA topoisomerase 3-alpha; DNA topoisomerase III alpha; Top IIIa; TOP3; TOP3A; topo III-alpha; topoisomerase (DNA) 3 alpha; topoisomerase (DNA) III alpha; topoisomerase 3 alpha; ZGRF7; zinc finger, GRF-type containing 7 | |
| Top3a | |
| IgG | |
| Antigen affinity chromatography, Protein A | |
| Antibody |
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